Autocrine interleukin-1 beta regulates both proliferation and apoptosis in EL4-6.1 thymoma cells
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چکیده
منابع مشابه
Autocrine Interleukin-lp Regulates Both Proliferation and Apoptosis in EL4-6.1 Thymoma Cells
We demonstrate here that EL4-6.1 cells, a mouse thymoma that expresses high levels of membrane interleukin (IL)-l receptors, produce IL-IB as an autocrine regulatory factor. Endogenous IL-IB sustains both proliferation and apoptosis: during the exponential phase, it mainly promotes proliferation, while during the plateau phase of cell growth, it induces death by apoptosis. Additionally, we show...
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ژورنال
عنوان ژورنال: Blood
سال: 1995
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v85.12.3532.bloodjournal85123532